US cable giant Comcast has unveiled its own homeb

first_imgUS cable giant Comcast has unveiled its own home-built DOCSIS 3.1 cable modem and said it will go into production this year ahead of deployment in 2016.Comcast, which has been a driving force behind development of a number of the cable industry’s next-generation technologies, including the Converged Cable Access Platform (CCAP) and the RDK software bundle for consumer premises equipment, has combined a WiFi router, IP video technology and integrated home automation and security capabilities in the device, according to CTO Tony Werner’s blog posting.Werner said that the Comcast Gigabit Home Gateway could deliver speeds in excess of 1Gbps, thanks to DOCSIS 3.1, and that it would be backward compatible with the DOCSIS 3.0 standard to enable deployment in the near term. The device integrates the PowerCloud home network control and monitoring technology acquired by Comcast in 2014, and also uses the RDK-B open-sourced software developed by Comcast with contributions from companies including Cisco.last_img read more

Atlice has abandoned its attempt to acquire the le

first_imgAtlice has abandoned its attempt to acquire the leading Portuguese broadcaster and production group Media Capital in the face of lack of progress to secure regulatory approval of the deal.Altice said that, one year after signing the contract and with no outcome of the regulatory process in site, it was calling time on the merger.Altice has been trying to secure a green light from the Portuguese competition authority, the Autoridade da Concorrencia (AdC), for the acquisition of Prisa’s majority stake in Media Capital in the face of hositility from politicians, other operators and media groups in the country.The telecom giant, which owns the former PT Telecom/Meo telecom operator in Portugal, said that the decision to call a halt came after the contractual deadline for the agreement between it and Prisa was extended for two months in April to allow further time to secure approval from the antitrust watchdog.Altice laid the blame for the collapse of the merger squarely on the regulator. It said that it had proactively set out remedies in line with European Industry practice in the sectore but had encountered a “complete lack of openness” on the part of the AdC, despite both parties to the agreement being initially “confident of a positive assessment”.Atlice said that the AdC had not taken the necessary decisions to enable the impelemtnation of the agreement in a timely manner. It said that it had presented a comprehensive set of long-term commitments that could be monitored by an independent trustee, including the separation of various business areas, ensuring the TVI channel was avaialable to competing platforms at a far and non-discriminatory price and renunciation of exclusivity regarding conent.The telecom group said that “an opportunity has been lost” to create an integrated media and telecom company in Portugal that could compete with international digital giants, and pointed to the US court decision on the AT&T-Time Warner deal as evidience for the case that consolidation is vital if traditional media companies are going to survive competition with internet companies.The AdC initially opened its in-depth probe into the merger in February, after concluding that there was evidence that it could give rise to “significant impediments to competition” in several markets.last_img read more

The private panel that began with three key speake

first_imgThe private panel that began with three key speakers at the April 27-29 Casey Research Recovery Reality Check Summit continues with a second installment in today’s Energy Report. This exclusive features Casey Energy Opportunities Senior Editor Marin Katusa, Global Resource Investments Founder and Chairman Rick Rule and Casey Research Senior Editor Louis James, turning their attention to oil and natural gas prices and opportunities in equities. Source: Karen Roche and JT Long of The Energy Report (5/10/12) The Energy Report: Since we last talked in November, oil went from $90–110 per barrel (bbl). Has it established a floor that will stick? Or, as Porter Stansberry predicted during the summit, is it getting ready to crash? He said that using the same sorts of technology that brought on the glut of natural gas will lead to finding too much oil and driving its price down. Marin Katusa: Porter was basing his comments on the success of shale gas in North America, and with that you have natural gas liquids and some oil. In North America, gas became a victim of its own success, worsened by a warmer-than-expected winter. But understand that gas, in general, has very localized markets. When it comes to the oil sector, people think Exxon Mobil Corp. (XOM:NYSE); Royal Dutch Shell Plc (RDS.NYSE.A/B) and ConocoPhillips (COP:NYSE) are the biggest players. The big players are actually the national oil companies (NOCs)—Saudi Aramco, Petróleos Mexicanos (Pemex) and Petróleos de Venezuela, which are not reinvesting in operations and exploration. Their production is decreasing as a result. Cantarell, in Mexico, is one of the greatest oilfields in the world, but it’s decreasing by 3.5% every year. The NOCs are distributing profits to fund massive social programs. For instance, more than 55% of Venezuela profits from oil-funded social programs. By the way, America imports more than a million barrels of Venezuelan oil each day and pays a premium over what it pays for domestic oil. But that’s another story. I don’t necessarily agree that the same reasons why natural gas in North America went under $2 per thousand cubic feet (Mcf) would apply globally. India is signing $14–$15/Mcf and more; Japan is at $15/Mcf-plus. It’s twice that in Europe. So North America is a unique case; the rest of the world is nowhere near that when it comes to shale exploration. TER: Will that change when the U.S. starts exporting in 2015 or so? MK: I think 2015 is a very aggressive timeline. Eventually, the market will fix itself. But to say that oil will go to $40/bbl by Christmas? I wouldn’t take that bet. That said, for two years we’ve been using $60/bbl oil for our equations. We publish the best netbacks in the business every quarter. So if a company can make money at $65/bbl oil, it will make a lot of money at $105/bbl oil. But if you invest in companies that need $90/bbl oil to break even, you’re not going to do so well. TER: You said the market will fix itself. Will oil go down to, say, that $60/bbl you’ve been using? MK: Everyone isn’t paying $103–105/bbl. Because of the massive differential for selling less, the Canadian oil sands producers are selling as low as $63/bbl. In the Bakken, they’re selling for $72/bbl. So it finds its equilibrium. In the Canadian oil sands, existing production can be profitable at $60/bbl, which we’ve been saying for a couple of years. New production, if it’s open pit, it needs $90/bbl oil to be economic due to the massive inflation in equipment, trucks, tires and people. TER: Why do we quote oil at $105/bbl if it costs $63–72/bbl? MK: A lot of people think that Suncor Energy Inc. (SU:TSX/NYSE) or any given oil producer is making $105/bbl for oil, but companies are selling their product for $63/bbl. It depends on the differential and Suncor’s selling price versus the West Texas Intermediate (WTI) crude oil price, which is the posted price. Gas producers in Edmonton are getting much lower prices than what’s quoted in the Henry Hub. The oil price in North America or the Brent price isn’t necessarily the same price a company is selling its oil for. Rick Rule: It’s pretty complex. What people think of as the posted crude oil price comes from either WTI or Brent. That used to be the way the world worked, but we have localized differentials now. One of the differentials that Marin was speaking about is the differential between light sweet crude and heavy crude. And the differentials widen and tighten depending on a variety of factors. For example, production efficiency in Venezuela, the traditional source of Gulf Coast sour crudes, is a factor. Transportation and infrastructure bottlenecks are factors. We’re now to the point where a critical pipeline from the Gulf Coast to the U.S. Midwest, which used to take imported crude into the Midwest, has been reversed because of production declines in Mexico and Venezuela, which encourage U.S. Gulf Coast refiners to take heavy crude out of Canada. All of this is what creates localized markets in oil. The international light sweet crude markets are very stout. Nigerian bonny crude and Brent crude’s international trade is marked by tightness as a consequence of declining supplies in traditional frontier market exporters, such as Nigeria as well as Venezuela and Mexico. The North American domestic market is ironically awash in oil as a consequence of three factors: The high price of gasoline has begun to destroy demand along with the weak economy. The incredible de-bottlenecking that’s gone on in the Athabasca tar sands has doubled tar sands production in four years. And the conjunction of technologies that Marin was talking about has produced a flood of shale oil, particularly in the Bakken. TER: But when the gas at the pump is up, the excuse they give is that WTI is at $105/bbl. That’s the logic presented to consumers. RR: I can’t speak to other parts of the country, but being an oil producer myself and a gasoline consumer, I’m certainly familiar with the California gasoline market. California municipalities constrain the construction of gas stations, so there are fewer and fewer outlets. Some communities that were really tough on how many gas stations they would permit have prices $0.25–0.30 per gallon higher than nearby communities that were more generous. On top of that, all the margins for producers, refiners and distributors that are built into the price of gasoline go to the government in the form of taxes. California is a high-cost refining environment, with high taxes and constrained competition. Gasoline demand in the U.S. has grown 1.2–1.3%, compounded for 29 years, and the United States hasn’t permitted a new refinery for 29 years. Maybe no new refineries would have been built anyway because refinery and marketing margins are so lousy. But that’s the picture. MK: Also, the older refineries need more downtime for maintenance. All these things factor into the equation, and that’s why you have high prices at the pump. In Canada, more than 50% of the price is taxes. Major global production is coming from these NOCs, which I call the New Seven Sisters.* *[Before the rise of the OPEC cartel and NOCs, the original Seven Sisters included Anglo-Persian Oil Company (now BP), Gulf Oil, Standard Oil of California (Socal), Texaco (now Chevron), Royal Dutch Shell, Standard Oil of New Jersey (Esso) and Standard Oil Company of New York (Socony) (now ExxonMobil). The Seven Sisters dominated the global petroleum industry from the mid-1940s to the 1970s, and up until the oil crisis of 1973, controlled about 85% of the world’s petroleum reserves – Editor.] Look at the coming nationalization of resources. Look at what’s happened in Argentina. The private companies, the Exxons of the world, risk their capital and their shareholders’ capital. When they have success, the country nationalizes these resources. So there’s another factor to take into account if you want to understand how tight the oil markets really are. TER: A number of people we’ve interviewed lately say the best bet now is to invest in the service companies—the drillers, pipeline builders and so forth. MK: Part of our portfolio in The Energy Letter is geared toward service companies, and certainly Kinder Morgan (KMP:NYSE), which is one of North America’s largest pipeline transportation and energy storage companies, has been very generous to our portfolio. In five months, there’s been over a 30% gain. But if you’re going to go into the service sector, you have to make sure about a company’s ability to cover its debt, because a lot of these services companies took on massive debt during the bull market and will blow up on it. TER: Looking for other potential investments, Louis, you said that the secret is to figure out what real stuff people need, because it will retain value. When prices on valuable stuff go down ridiculously, it’s a godsend, because you can buy when it’s cheap and sell when it’s expensive. Is the stuff people need cheap now? Louis James: Stuff is not really cheaper. There is deflation in some asset classes and some equities, but life for the average Joe is not cheaper and commodities in general are not cheaper. Oil is still above $100/bbl. When commodities have not lost ground but the equities have, that’s an alligator jaw pattern. I’m not speaking as a technical analyst—that’s just a metaphor. But it’s actually fantastic if you have high, driving prices in the commodities, and you find good, cheap companies with good management, money in the bank and the wherewithal to weather the storms. I also think we’ll see more volatility, and the chances of seeing much lower prices are pretty good. When a bear sentiment grabs the market, it takes everybody down, both the best and the worst players. If you have the courage to face it, that’s very good news. If you’re new to the game, you can get fantastic buys on things that others have identified as great plays, already worked on and de-risked. If you’re already long, it’s a matter of self-discipline, which few investors have. Most of them get burned again and again. They buy high when everybody else is buying. They feel confident. They jump in. Things turn against them. The tide goes the other way. They get scared. Everybody else gets scared at the same time and they get creamed. Investors need self-discipline, belief in what they’re doing and they need to know why they’re buying something to be able to happily take those shares off weaker hands. I think there’s a good chance we’ll see much more of that over this summer and I’m looking forward to it. After the sector bounced back from 2008, I wrote that we should be so lucky as to have another one. TER: Speaking of lower equity prices, Marin, last fall you told us that quantitative easing was deflating equity valuations. “He who has cash will be king,” you said, “because he can afford to buy discounted stocks. If you do your homework and be sharp you’ll make a fortune in the next three years.” Is that still the case? Or are we too late? MK: I still believe we’re in deflating equity prices. By mitigating risk, being strategic, always taking Casey free rides, the portfolios for 2011 for both the Casey Energy Report (CER) and Casey Energy Confidential (CEC) gained over 20%. And Q1/12 was over 20% for both newsletters, too. Throughout the year, a few of our buys had massive gains—like Poseidon Concepts Corp. (PSN: TSX), TAG Oil Ltd. (TAO:TSX; TAOIF:OTCQX;) and Africa Oil Inc. (AOI: TSX.V). Did we sell too early? Yes. But so what? We reduced our risk. We made money. We lived to see another day. And with one of them, we now have a dividend for free and the company’s growing. So if you do your homework and buy good companies, you can do well. I don’t think you’re too late at all. The 300+ investors who attended the 3-day Casey Research Recovery Reality Check Summit discovered a multitude of natural resource investing strategies during daily Gold and Resource Stock Roundup sessions.  These sessions featured Rick, Marin, Louis and Jeff Clark, senior precious metals analyst at Casey Research, who together revealed their favorite natural resource stocks to invest in now.  You can hear all of their  recommendations, as well as every recorded summit presentation—over 20 hours in all—with the  Casey Research Recovery Reality Check Summit Audio Collection. Founder and CEO of Global Resource Investments and President of Sprott Asset Management U.S.A, Rick Rule began his career in the securities business in 1974 and has been principally involved in natural resource security investments ever since. He is a leading American retail broker and asset manager specializing in mining, energy, water utilities, forest products and agriculture. Rule’s company has built a sterling reputation for its specialist expertise in taking advantage of global opportunities in the resources industries. In 2011, Rule closed a landmark deal with Eric Sprott, Founder of Sprott Inc., another famous powerhouse in the arena. Sprott Inc. offers resource-oriented investors opportunities in segregated managed accounts, mutual funds, hedge funds and private partnerships. The collective organization offers unparalleled expertise and access to investment opportunities in all resource sectors. Sprott Inc. manages a portfolio of small-cap resource investments worth more than $8 billion and boasts a workforce of more than 130 professionals in Canada and the U.S. Louis James is chief metals and mining investment strategist at Casey Research, where he is also the senior editor of Casey Investment Alert and Conversations with Casey. When not in meetings with mining company executives in Vancouver, B.C., James regularly travels the world evaluating highly prospective geological targets and visiting explorers and producers getting to know their management teams. For more than 25 years, Casey Research, headed by investor and best-selling author Doug Casey, has been helping self-directed investors to earn returns through innovative investment research designed to take advantage of market dislocations. Investment Analyst Marin Katusa is the senior editor of Casey’s Energy Opportunities and Casey’s Energy Confidential. He left a successful teaching career to pursue what has proven an equally successful—and far more lucrative—career analyzing and investing in junior resource companies. With a stock pick record of 19 winners in a row—a 100% success rate last year—Katusa’s insightful research has made his subscribers a great deal of money. Using his advanced mathematical skills, he created a diagnostic resource market tool that analyzes and compares hundreds of investment variables. Through his own investments and his work with the Casey team, Katusa has established a network of relationships with many of the key players in the junior resource sector in Vancouver. In addition, he is a member of the Vancouver Angel Forum, where he and his colleagues evaluate early seed investment opportunities. Katusa also manages a portfolio of international real estate projects. Want to read more exclusive Energy Report interviews like this? Sign up for our free e-newsletter, and you’ll learn when new articles have been published. To see a list of recent interviews with industry analysts and commentators, visit our Exclusive Interviews page. Disclosure: 1) Karen Roche and JT Long of The Energy Report facilitated this panel discussion. They personally and/or their families own shares of the following companies mentioned in this interview: None 2) The following companies mentioned in the interview are sponsors of The Gold Report: None. 3) Rick Rule: I personally and/or my family own shares of the following companies I mentioned in this interview: None. I personally and/or my family am paid by the following companies I mentioned in this interview: None. 4) Louis James: I personally and/or my family own shares of the following companies I mentioned in this interview: None. I personally and/or my family am paid by the following companies I mentioned in this interview: None. 5) Marin Katusa: I personally and/or my family own shares of the following companies I mentioned in this interview: None. I personally and/or my family am paid by the following companies I mentioned in this interview: None.last_img read more

Louis James Doug a lot of our readers have asked

first_imgLouis James: Doug, a lot of our readers have asked about getting a second passport. I realize this is a large and complex issue – several issues, actually – but would you care to go over the basics of where to go and what to do? And for those not already thinking about this, why? Doug Casey: Sure. We’ve talked quite a bit about the increasing urgency of getting some of your assets out of your home country, especially if it’s the United States. We’ve talked about having stores of precious metals in safe places abroad, and setting up bank and brokerage accounts abroad as well. I’ve said that safest way to store wealth abroad is to buy property, which can’t be seized by your home country without an act of war. The purchase of real estate solves several issues all at once. But that’s all about protecting assets; to protect yourself, getting a second passport is unfortunately very important. LJ: Why unfortunately? DC: Because you shouldn’t have to need government papers to live as you please. It used to be that a passport was a document that a ruler of one country would give to a traveler to ask the rulers of other countries to assist him in his travels. Now, instead of a convenience, it’s become a required permit for travel. It’s degrading and actually runs counter to the whole idea of the thing. The original purpose of a passport has been turned upside down. LJ: Passports are becoming a world ID card – and they will be, once the governments all link up their databases. DC: That’s exactly what they are, and I’m sure it’s going to get worse. It’s funny the way people treat these things like some sort of holy relic, or magical object – they are nothing but another government ID. But since they are necessary in today’s world, you ought to have several of them, for your own convenience. If nothing else, it prevents any one government from basically placing you under house arrest by taking your passport away from you. LJ: Do you really think of it mostly in terms of convenience? Or do you sometimes think about the potential for physical danger, should you find yourself in an Achille Lauro-type situation in which violent people who hate Americans select US passport holders for abuse? DC: That’s definitely a good reason for Americans to have a second passport, and increasingly for others, now that the war with Islam is under way. If you ever get caught in harm’s way, it helps that nobody starts by shooting all the people from countries they’ve never heard of. LJ: Round up all the Uruguayans! DC: Right – that just doesn’t happen. Another reason – certainly if you’re an American – is that nobody anywhere in the world wants to open a bank account or a brokerage account for you. It ranges from impossible to hard and inconvenient. It’s a subtle and indirect form of exchange control that the US has already imposed. I have no doubt controls will become much more formal and serious in the near future. LJ: Are you saying that if I go to Switzerland, and I look and sound like an American, but have a Mexican passport, they’ll open a bank account for me? DC: It depends. Here in Uruguay, where I’m still hanging out on the beach, I went with a friend from South Africa to open a bank account, using her South African passport. I didn’t say a word, so I could have been a South African too, for all they knew. Still, the bank officer asked her: “Are you also a US citizen?” and “Are you resident in the US?” LJ: The long arm of Uncle Sam keeps getting longer. DC: It really is getting harder and harder. Banks really don’t want the aggravations that come with dealing with “US persons” and their bullying government. Of course, it’s all going to eventually backfire on the US, but in the meantime it’s going to get worse. LJ: Yes – I don’t like it when they ask for my passport at hotels, and I hate it when they say they have to keep it. DC: As well you should, for all kinds of reasons. You never know how good the security at the hotel is, and the inconvenience of a lost or stolen passport is substantial. I’d say a second one is a good thing to have, just on principle. An alternative would be to get documents from some of those people trying to set up new countries, like Sealand, the WWII gun platform off the coast of England taken over by Roy Bates. I spent an afternoon with him once, but foolishly never signed up as a citizen. Oh well… Other outfits sell reproduction passports of defunct or renamed countries like Rhodesia and British Honduras. LJ: I shudder to think of what “inconvenience” means to a man who finds it amusing to argue with immigration officials in back rooms in flyspeck countries… But at any rate, mentioning purveyors of passports from defunct countries underscores the importance of telling our readers that there are a lot of scams out there, and that it pays to be very skeptical of websites that claim to be able to set you up with documents, corporations, and bank accounts overseas. There are freelance thieves to worry about, and worse – governments trying to entrap so-called tax evaders and money launderers. There’s no need to take such risks when you can go to any of the many countries that encourage immigration and permanent residency, and acquire government-issued documents legally. DC: Yes, these are indeed shark-infested waters. You really have to do things in a totally correct and proper way. For instance, there always seem to be people running around who have passports stolen from the issuing agency, and some fools buy them, not realizing they’ll not only lose their money, but might wind up in jail besides. But, even among perfectly legitimate documents, not all passports are created equal. LJ: Why would that be? DC: The defining characteristic of a “good” passport is how much visa-free travel it allows. And by that I really mean visas that have to be applied for, and approved, before the trip begins, as opposed to those issued at the border. Avoiding those is the real key value. In spite of its reputation, a US passport is by no means the best one to have. First, if you have one, you’re a US taxpayer, which is very inconvenient, but it also means you need visas for a lot more countries than you would with some other passport. Argentina, Chile, and Brazil, for instance, all charge Americans about $150 to issue a visa. It’s a perverse form of reciprocity, as that’s what the US government charges their citizens. It’s the same kind of thinking that starts trade wars, and I expect more of it in the years to come – but that’s another subject. Speaking of South America, two passports that are relatively quick and easy to get are those from Uruguay and Paraguay. Both countries are members of the Mercosur group of South American countries, which offers some additional advantages to their nationals. One of the best, I’m given to understand – and this is constantly changing – is a Singapore passport. I also understand that Singapore has a number of ways to become a citizen in a relatively short period of time. LJ: What are some of the shortcuts to second citizenship? DC: One of the best is if you have parents or grandparents from a country that will give you citizenship on that basis. Ireland and Italy are known for this. It’s true, under some circumstances, for the UK as well. Saint Kitts is a relatively easy place to get a passport quite quickly, but it involves a significant investment that adds up to a couple hundred thousand dollars. Selling IDs is a significant source of income for the island. And of course, in a number of countries you can obtain citizenship, and hence documents, relatively easily by marrying a national. Brazil is one, and a Brazilian passport is not a bad one to have. There’s information on this out there, but there have been scam reports done on this subject and many other sources that are simply unreliable, so watch out. I don’t think there’s ever been a truly definitive study done on all the ways, in all the 200 or so countries in the world. I believe my book The International Man was the first to really explore the ground – but it’s long out of date. Even if there were a current book, it would have to be updated monthly to be of real value – governments are always changing their rules. And when it comes down to the particulars of a given situation, you’ll want to hire a tax attorney and maybe an immigration one as well, to make sure everything is done correctly. It’s generally better not to try for shortcuts, but to move to a place you like living in, at least part of the year. Operating through the established, legally recognized channels, you can get a passport in two to five years. LJ: Okay. And, to be clear, the US allows second citizenships? DC: Yes. Many countries don’t, and are strict about it. Others don’t, but look the other way. You may feel you want to keep your US documents for various practical reasons, but remember that keeping your US citizenship means remaining a US taxpayer, which is most undesirable. LJ: I read that if your income is less than $100,000 per year and you live abroad, it’s not taxed, so maybe the tax issue is less important to people who earn less than you? DC: That’s true, but that exemption only applies only on income earned outside the US You still pay capital gains taxes, and taxes on US-sourced income. I also understand that under current law, until 2013, there’s a $5 million exemption on appreciated expatriated assets. That means there’s a window closing soon on some of the benefits of getting rid of your US citizenship. LJ: Any reasons other than taxes you’d want to get rid of your US citizenship? If I were young enough, I’d worry about conscription, for example. DC: That’s a very good reason. More generally, as long as you’re a citizen of a country, that country’s government is going to treat you like its property. So, if you are going to be a citizen of any place, which is unfortunately necessary, it’s better to be a citizen of a small and backward country, or one that just doesn’t have the ability or interest to monitor all of its citizens like prison inmates, as the US does. LJ: I hear that. It’s such a pity that America the beautiful has turned into the United State and is rapidly marching down the road to serfdom… I really loved America. DC: Nothing lasts forever, Lobo. It’s suicidal to let sentimentality blind you to reality. But, eternal optimist that I am, it’s always good to look at one of the major bright sides of the ongoing financial and economic collapse. Namely that the governments of most advanced nation-states are bankrupt. There’s a chance that some of them will be forced to cut back on their most noisome activities. There’s even a chance that one or two will be completely hollowed out and will exist mostly in theory, like Rome in the late 5th century. It’s very hard to predict what will happen, so it’s best to have a Plan B. And a Plan C. Unfortunately, most people have a medieval serf mentality – although they don’t know it, and probably wouldn’t admit it even if they did – and have no plan at all, because they think everything is fine. LJ: I agree. And you know I’m diversifying out of the US as well. Any other essential points? DC: Yes, remember that getting a second passport is just part of a larger “permanent traveler” strategy. The ideal is to live in one place, have your citizenship in another, your banks and brokers in other jurisdictions, and your business dealings in yet others. That makes it very inconvenient for any one government to control you. You don’t want all your eggs in one basket – that just makes it easier for them to grab them all. I understand it may not be easy for most people to structure their affairs that way. That’s exactly why most serfs stayed serfs; it was hard and scary to think of anything other than what they were told they should do. LJ: Understood. Thanks for the guidance. The more of your wealth you have in your home country, the greater the risks to your capital. That’s why it’s critical to start protecting your assets by moving them abroad as soon as possible. To help you do just that, Casey Research is hosting a web video event at 2 p.m. EDT on Tuesday, April 30. Internationalize Your Assets features investment experts Doug Casey, Peter Schiff, Mike Maloney, and more. This must-see webinar will reveal offshore strategies you can easily implement to protect what’s rightfully yours. Click here for details and to register.last_img read more

first_img— — In those days the border was a more fluid concept. In 1917, Pershing lead 5,000 US cavalrymen deep into Mexico, chasing Villa after a raid he made into the US. That was about the time of the famous Zimmerman telegram, where the Germans promised help getting Texas, New Mexico and Arizona back to Mexico, if the Mexicans declared war on the US. That was one reason the Americans entered WW1. No matter… the Mexicans will get that land back without a formal attack.Justin: Interesting indeed. But back to the current situation…Doug: Right. Pershing and horse soldiers are long gone. Let me start by saying that the national guardsmen Trump proposes are basically weekend soldiers. These guys would rather be at home. They’d rather be working their day jobs. They’d rather spend time with their families. They’re not going to be happy about this.Plus, they’re unlikely to serve any useful purpose. Think about it. If they’re confronted by a large group of migrants, how are they going to stop them? Is it going to turn into a game of Red Rover? Or maybe a pushing contest?The only way they could stop a big group of migrants crossing the border is with real violence. But they won’t do that. That won’t happen.In other words, a large group of say 10,000 to 20,000 people, in unison, could easily walk across the border. Plus, understand that the people behind this mass migration aren’t stupid. They understand the dynamics. They know that a hundred migrants would just be a nuisance, to be rounded up and put in jail. You need the military principle of mass.Next time, maybe they’ll show up to the border with 50,000 people. That would be the equivalent of the Goths at Adrianople. That was 378 AD. After that, the barbarians totally inundated the Roman Empire from every angle. And in a generation they controlled every aspect of the Empire.If I wanted to collapse the US, that’s how I’d do it. Who needs the risks and expense of a conventional war? It would be neither hard nor very expensive to get a couple hundred thousand Salvadoreans, Hondurans, and what-have-you—not to mention Mexicans—to just human wave across the border. That would show the US is incapable of stopping anybody—except harassing some polite European tourists in airports, or polite Canadians driving across by car.Of course, there’d be a counter reaction. But things could easily spin out of control.Justin: And who do you think is behind all of this?Doug: Non-governmental organizations (NGOs) are certainly behind these migrants crossing the border. Poor peasants from Central America, or wherever—poor people and miscreants will show up from all over the world once the cat’s out of the bag—can’t act en masse. Today these people couldn’t cross the American border on their own. Or at most in onesies and twosies.Migrants don’t have the resources to support themselves. So they’re obviously getting help and funding from outside sources. I suspect it’s coming from NGOs. These people are politically and psychologically committed to destroying Western Civilization. And the average American or European has become so guilt-ridden, self-effacing, and philosophically corrupt that they welcome them.So, again, what they’ll try is sending 10,000, 50,000, or 200,000 people across the border. You couldn’t stop that many people. I don’t care if Trump puts up the National Guard; that will just add to the embarrassment. They’d just walk across the border, unless they’re machine-gunned. But the Guard is obviously not going to do that.I’d also gather as many pregnant women into the migrants as possible, both to create sympathetic photo-ops for the invading mob, and so their children could act as anchor babies. It would create chaos, which is exactly the desired effect.Most people don’t realize that the invasion that followed the Battle of Adrianople brought the Roman Empire to its knees within 30 years… They think that Rome fell in 476 AD, but that’s actually a meaningless date. It collapsed 60 or 70 years earlier, when the migrants totally washed everything away. Rome was just a shadow of its old self by the late Third Century. The army was mostly foreigners. Being a citizen no longer meant much. The government was bankrupt. The old values were being replaced by a new religion. There’s much more to be said. I suggest you look at a long article I did on this in December 2013 here.That exact same thing could happen in the States. And I don’t doubt that someone’s planning that already. There’s never been a better time to become a marijuana millionaire. The Pot Stock Millionaire Summit is willing to guarantee that they can give you the chance to see 500% gains from each of the 5 marijuana stocks that will be discussed during the Summit. The Summit is this Thursday, 8pm Eastern. It’s FREE for you to attend. Click here to reserve your spot to the event and get additional free training. **** 24245678 **** Justin’s note: Donald Trump wants to put 2,000–4,000 troops on the U.S.–Mexico border. And it’s no secret why he’s doing this. Trump wants to secure the borders. He believes that the “security of the United States is imperiled by a drastic surge of illegal activity on the southern border.”To be fair, this isn’t unprecedented. There have been three large-scale National Guard border missions since 2006. Still, I can’t help but wonder what might come out of this, given Trump’s strong views on illegal immigration.So, I called Doug Casey for his take on this issue…Justin: What do you make of this, Doug? Will deploying thousands of troops to the border curb illegal immigration?Doug: Well, it looks like what could have been a crisis has been temporarily defused. What might have been thousands of migrants rushing the border has apparently dwindled to a few stragglers. A non-event.But troubles on the Mexican border have a long and colorful pedigree. Especially starting from around 1912–1918. For one thing, one of my favorite authors, Ambrose Bierce, went to join Pancho Villa’s forces in 1913. He was in his 70s, and it was his way of checking out.There were some great movies made about that time and place, as well. Vera Cruz, with Burt Lancaster. The Professionals, with Burt Lancaster and Lee Marvin. And possibly my personal all-time favorite, The Wild Bunch, with William Holden. There’s even a fun comedy about the era, Three Amigos, with Steve Martin. Recommended Link What does 24245678 mean to you? For most folks, it’s just a bunch of numbers. But for you, knowing how to spot it could mean an easy $9,000 payout in the next few days. Click here immediately to see why. It’s TRUE! The Pot Stock Millionaire Summit is Offering the “5 for 500%” Pot Stock Guarantee As always, if you have any questions or suggestions for the Dispatch, send them to us right here.In Case You Missed It…A technology is being tested that has the potential to permanently cure thousands of diseases. It could even guarantee America’s energy independence for decades to come. It sounded too good to be true. But then we watched this presentation. Justin: Yeah, I’ve read a lot about NGOs doing the same thing in Europe. They’re literally moving Africans by the boatload to Europe, specifically Italy.Doug: These people have to be getting assistance. It’s not like they possess outboard motors, sails, or the skills to cross the Mediterranean. That’s serious business. So, they’re obviously getting help. But this has been happening for years.But who’s behind all this? Where’s the money coming from? We need to ask ourselves these questions because NGOs are destroying Western civilization. They’re run by busybodies looking to create chaos. And it’s in the interests of “charity.” Giving them money makes you a “philanthropist.”Justin: Why would they want to do that?Doug: It’s mostly a question of psychological aberration. Combined with perverse and bent philosophies. Universities today are filled with Marxist professors who despise Western civilization. Despite the fact Western civilization has brought us almost all the good things in life.It’s responsible for basically 100% of the world’s great literature, and 100% of the world’s great music. Free markets. Individualism. Liberty. The concept of human rights. The rule of law. Philosophy. Science. Technology. Almost all the noble ideas in the world. There are, to be sure, a few worthwhile things from other cultures. It’s been said that East minus West equals zero, but that’s going too far. I’m a fan of yoga, Taoism, and Oriental cuisine.Why would anyone want to destroy it? It’s a complete mystery to me. I don’t know what’s going on in these people’s heads. But I’ve spoken to people who hate Western civilization, and they’re apparently sincere about what they’re doing.So, maybe they’re just stupid. Look, I don’t care what their IQ score may be. These people are stupid on a very basic level.Justin: What do you mean by that?Doug: Well, we first need to define the word “stupid.” As I’ve said before, the best definition is an unwitting tendency to self-destruction; that’s what these people suffer from. Why? Perhaps they’re really very unhappy with themselves, but don’t have the courage or enough honest introspection to just put a gun to their heads. Hmm… maybe that’s another reason they’re universally antigun.There’s also a difference between intelligence and wisdom that’s lost on most people. Wisdom is the ability to calculate not just the immediate and direct consequences of actions. It doesn’t take much wisdom to make that calculation. The average six-year-old can do this. It’s not very deep.But you also must be able to contemplate the indirect and delayed consequences of your actions. And the people who run these NGOs seem incapable of that. They have absolutely no wisdom.That makes them stupid in my book. You could also say that they’re evil. But that word has also been discredited. A lot of religious types like to bandy it about. Their idea of “evil” is whatever goes against their god.But I’ve read the Bible. I’ve read the Quran. And I don’t think what passes for evil in those religious texts washes, quite frankly. To me, evil is being purposely destructive. And that’s what a lot of people who join these NGOs are.Sure, they pretend to be nice. They act like they’re doing all these wonderful things but they’re destroying civilization. They just can’t see it because they lack wisdom.The people populating NGOs and governments aren’t necessarily evil—even Mao, Pol Pot, Hitler, and Stalin felt they were good guys, doing the right thing. They’re just thoughtless and stupid.Justin: What about a desire for power control? It seems like that’s why a lot of people get involved in government and organizations like NGOs. They believe they’re best suited to shape society.Doug: You’re absolutely right. And they take control of society in many ways. They’re much more interested in controlling other people than they are in controlling physical things, however.Many of these same people naturally find their way into government. They enjoy pushing their fellows around. But, surprisingly to me, anyway, the average person seems to want that. They want a strong leader. They like hierarchy. They don’t mind being under the control of other people.All these socialists, social democrats, liberals, Democrats—their names are legion—think they’re doing the right thing. They think they’re being moral. And you can’t convince them otherwise. Intellectual arguments are useless against these people. It’s a psychological problem, not an intellectual one.You can’t make an intellectual argument to a mob.Justin: Thank you for taking the time to speak with me today, Doug.Doug: You’re welcome.Justin’s note: Most know Doug as a legendary crisis investor. But he’s also a “marijuana millionaire.” And tomorrow at 8 p.m. ET, he’s joining me and Crisis Investing editor Nick Giambruno to discuss why investors will be handed a rare second chance at investing in the marijuana market.This second wave is expected to be 8 times bigger than the first, when pot stocks were gaining 3,986%, 17,300%, 69,000%… even 299,000% and 399,000%. To hear from Doug himself on this exclusive FREE event—and why the time to strike is now—click here.Reader MailbagToday, a couple readers write in disagreeing with Doug’s take on nation states…I think “leave states and people alone” is always the best if done by example. What you are advocating is a loss of borders which is the moral equivalent of vanquishing one’s “body” (or your rights end where my body begins and vice versa), in favor of being “bodyless”. You cannot do away with the individual “anything”. A forest is a bunch of individual trees, first, last, and altogether. I don’t think the state is dead, but being transformed into its natural place, sovereign but equal nations.People right now can home school. People right now can form associations. People right now are waking up to this. People right now are beginning to see and not participate in the bloated state. But you seem to be advocating world government, at least you did in “part l” of your article. And, Doug, that is dangerous. And if your ideas don’t come about naturally with time, then world government it will be. A state much more horrid than nation states. And that is why I don’t agree. Westphalian National, sovereign states must be the next step or your ideas (which in and of themselves I agree with) will never come to pass. So please stop going around declaring that the “bordered” state, like the “bordered body” is dead. – Kay While there is some interesting material in this article, this statement is just very stupid: “Sure, he’s (Trump) done some pretty stupid things; his foreign policy of late borders on the criminally insane.” What things were “stupid”? I am not an American, so please tell me: Are you used to making empty statements and getting away with it without a challenge? And what about “his foreign policy of late ‘bordering’ on the ‘criminally insane’”? Challenging North Korea’s Kim Jong-un until he came to his senses? Bombing Syria for using chemical weapons?If you wish to consider gutless pile of sh*t foreign policy, look no further than the totally gutless wonder and complete pathological liar, Barack Obama, who like George W. Bush and Bill Clinton lacked the courage to challenge North Korea. As to the southern U.S. border he is entirely right, you need a wall. When you began spouting this drivel you destroyed the credibility of what you said earlier about nation states. – Rob Recommended Linklast_img read more

A new research centre that plans to create a centr

first_imgA new research centre that plans to create a centre for “disability expertise” on the Olympic Park – as part of the London 2012 Paralympics legacy – has faced questions about its commitment to collaborating with local disabled people’s organisations (DPOs).The Global Disability Innovation Hub (GDIH) wants to spread innovative ideas across inclusive design, assistive technology, sport, arts and inclusive development and use the new centre as a “springboard for change” to improve the lives of disabled people in the UK and internationally.GDIH says it wants to ensure that disabled people are involved in the leadership of all of its programmes and to “promote that ethos and that way of working” internationally.Its aim, it says, is to “change the way we think about disability through co-design, collaboration, and innovation”, and to become “the leading place to come to research, study, practice and share disability innovations”.This week, the hub’s director, Vicki Austin, told Disability News Service (DNS) that she wanted GDIH to develop into a global centre for “disability expertise”, drawing on local communities, DPOs and disabled people.The hub launched last September, but only appointed its 15-strong board of directors – two-thirds of whom are disabled people – last week.It is moving its current base to University College London’s (UCL) new campus on the Olympic Park in east London.But despite its commitment to ensuring that disabled people lead its programmes, there are questions over its apparent failure to work with local disabled people and DPOs.When asked which DPOs it had worked with since its launch, Austin mentioned Together! 2012, which is led by the disabled artist and author Dr Ju Gosling, and has been working since the Paralympics to make the main London 2012 host borough of Newham into an international centre of excellence for disability arts.Together! 2012 is the most prominent DPO in the borough, and the only cultural organisation in east London to have been developed in response to the Paralympic legacy, while Gosling herself has an international reputation as a disabled artist, based in Newham, and is a leader on work looking at the relationship between disabled people and technology.But Gosling disputed Austin’s claims that the hub had been working with Together!, and said she had in fact been frustrated by her attempts to set up a meeting with GDIH, and had been trying to do so since January, in a series of emails seen by DNS.Her last emailed attempt to set up a meeting was on 16 May, which has still not received a reply from GDIH.She said: “They haven’t made any contact with us, and we have tried and tried and tried.“I find it discourteous and disrespectful and very disappointing. They clearly don’t know what co-production means.”A spokeswoman for the hub did not dispute the six-month delay in arranging a meeting, although she claimed that Austin had had “discussions” with Gosling as the hub was being developed.Austin said that GDIH had also been working closely with members of the Olympic Park’s built environment access panel (BEAP), and that it had been using them “as our initial sounding board”, as an interim arrangement before its board was appointed.One meeting was apparently held in the hub’s current home on the Olympic Park, so panel members could meet the team, while the panel’s chair, Peter Lainson, is a member of the hub’s working group, and two of his fellow disabled panel members have now been appointed to the GDIH board.But DNS has spoken to one member of the panel who said they were surprised to hear that GDIH was claiming such a close connection with BEAP, and believed the panel had not been involved with the hub in any significant way.The hub emerged from work at UCL and has some post-London 2012 funding from the London Legacy Development Corporation, although that is due to run out next year.None of GDIH’s other founding partners – the charity Leonard Cheshire Disability, the University of the Arts London’s London College of Fashion, Loughborough University in London, Saddler’s Wells Theatre, the Helen Hamlyn Centre for Design, and London’s Victoria and Albert Museum – are user-led organisations.The GDIH board will be led by the disabled Conservative peer Lord [Chris] Holmes, former disability commissioner for the Equality and Human Rights Commission, and London 2012’s director of Paralympic integration.He said he was “delighted” to be “part of a project with such potential to transform lives”.He said: “I have personally benefited from assistive technology and believe truly inclusive design not only removes barriers to disabled people but also, essentially, benefits everyone by leading to ground-breaking technological solutions or applications and truly excellent design.”Early GDIH projects include working with an “innovation lab” set up by a disabled people’s organisation in India and the International Committee of the Red Cross to develop new products to help disabled people, particularly in the global south.The hub is also involved in the development of a masters programme in disability design and innovation, which will begin in September 2018.Another project is the development of a digital/audio “wayfinding” tool that would help blind and partially-sighted visitors find their way around the Olympic Park.Austin said a crucial part of its approach was to ensure that disabled people were involved in leading its programmes. She said: “If there is an opportunity to amplify that message, and also the talents of those people, then that is what we intend and want to do.“We are particularly interested in harnessing the power of technology as it develops and a lot of that technology is being developed in institutions by non-disabled people.“If we are able to challenge some of that and engage people in both academic and non-academic programmes and also challenge some of the academic approaches in a way that puts co-creation and co-design right at the heart, not only are better products made but also it challenges the status quo.”Next month, the hub will host a disability innovation summit, running alongside the 2017 World Para-Athletics Championships, to “explore research and ideas, looking at innovation in tech, design, development, culture and art”.Picture: Lord Holmes at London Tech Week, after the announcement that he would be chairing GDIHlast_img read more

First Tumblr Now Hulu Oh My Whats Driving Yahoos Startup Appetite

first_img 2019 Entrepreneur 360 List First Tumblr, Now Hulu, Oh My! What’s Driving Yahoo’s Startup Appetite Next Article –shares Apply Now » Add to Queue Yahoo! CEO, Marissa Mayer Brian Patrick Eha May 28, 2013 Opinions expressed by Entrepreneur contributors are their own. Technology Under chief executive Marissa Mayer, internet giant Yahoo has been on a startup-buying spree, and it shows no signs of stopping. News broke over the weekend that Yahoo has offered to buy streaming video site Hulu for between $600 million and $800 million, depending on the overall terms of the deal.Hulu is currently the focus of a bidding war between Time Warner, Directv and other big players. Yahoo turned to Hulu after its plan to buy a majority stake in French video-sharing site Dailymotion was blocked by the French government earlier this month.Since Mayer took the helm last July, Yahoo has acquired 12 companies. Among them are news aggregation startup Summly, social-media platform Snip.it, video chat startup OnTheAir and microblogging platform Tumblr, which boasts over 300 million members. Since closing the Tumblr deal for $1.1 billion in cash last week, Yahoo has already bought another company: gaming software outfit PlayerScale. The four-year-old startup, which Yahoo bought for an undisclosed sum, creates tools for game developers, including analytics tools that can track player behavior.Related: In Yahoo Deal, Tumblr Becomes the Next $1 Billion Startup”Yahoo is pursuing a plan of diversifying its media business away from the pure Yahoo.com brand,” says Andrew Frank, who covers Yahoo as a media analyst for research firm Gartner. That means expanding beyond longstanding services such as search, news and email and getting into new areas such as social media and video, which could also help Yahoo branch out from its mostly advertising-based revenue. Such a plan, Frank says, is standard for maturing media companies that want to reduce risk and make their revenue more predictable.The desire to attract young users has also played a role, especially in the Tumblr acquisition, says Frank. And while Tumblr itself may not be a good platform for selling ads, due to the ad-free layout of its blogs, Frank believes its user data will prove to be a valuable resource to target advertising on other Yahoo properties. “If you can determine people’s interests based on their Tumblr experiences, then perhaps you can have better success targeting them with interest-based ads in other contexts,” Frank says.If purchased, Hulu would further the goal of diversifying Yahoo’s revenue, which Frank says has been almost exclusively dependent on advertising. Users of Hulu’s premium subscription service pay a monthly rate to watch movies and full episodes of television shows online. And the acquisition of a video service may help Yahoo compete with YouTube, which has proved to be an immensely lucrative property for Google.So what comes next? Frank was loath to speculate, but he said mobile needs to be a focus for Yahoo. He also mentioned ecommerce and social commerce as potential spaces for the company to enter. “There’s a lot of interesting areas that Yahoo could go into,” he says. “I don’t think there’s any shortage of opportunities.”Related: Yahoo Acquires Teen Entrepreneur’s News Gathering App, Summly 3 min read Image credit: mobil.stern.de The only list that measures privately-held company performance across multiple dimensions—not just revenue.last_img read more

Startup Culture 20 Why Kegs No Longer Cut It

first_imgStartup Culture Add to Queue Free Webinar | July 31: Secrets to Running a Successful Family Business Scott King Next Article Today’s startups have a problem, and no amount of free booze will solve it. Don’t get me wrong, I love beer — but it’s part of the problem.Related: 5 Hidden Dangers of a Stereotypical Startup CultureStartup Culture 1.0 was a response to a traditional workplace that stifled creativity and expression. Young professionals saw no value in wearing suits and working in cubicles. Organizations saw an opportunity to evolve, giving employees the freedom to work in a way that felt more like play. And, theoretically at least, they became more innovative, productive and attractive to top talent in the process.Hoodies replaced sportcoats. Scrum pits replaced cubes. Dogs roamed the halls. Ping-pong tables supplanted conference tables. And company kitchens filled up with healthy, local, organic, free-range snacks and kegs from local microbrews.There were no more off-sites in stuffy hotels; team building happened over whitewater rafting; volunteer teams travelled to Central America; and Frisbee in the park became a staple of work-optional Friday afternoons — all of which was delightful — until it went too far (see the recent Zenefits scandal).Worse, it became the new status quo.We now take for granted that we can wear jeans to the office and work from home when we need to. We no longer notice the keg in the corner of the kitchen — because frankly, no one drinks from it. Few people bring their dogs to work because, in reality, that’s kind of a hassle. And, while on-site yoga sounds good in theory, who wants to go all zen with their colleagues and then turn around and talk development capacity and budgets?When every company offers something, it’s no longer a perk.Indeed, when you strip away the cool “stuff,” we’re left with a culture that isn’t terribly different from the old-school system that it replaced. Sure, you no longer call your boss “Sir” or “Ma’am” when discussing your assignments — but you still get assignments. You may “download” on your projects in the “nerd lounge” with a latte from the new espresso machine, but you’re still told what to do and, largely, how, when, where, and with whom to do it.This is the issue with Startup Culture 1.0. The clothes, the offices, the rules may have changed, but the way work gets done did not. The next evolution of startup culture — let’s call it Startup Culture 2.0 — will implement a whole new set of perks that are significantly harder to provide, but are much more valuable when done right.Startup Culture 2.0 will be a fundamental shift in how we think about people. Instead of changing the lines we draw around them, we’ll remove the lines altogether.Related: Creating The Right Culture For Startup SuccessStartup Culture 2.0 puts the “people are our best asset” cliché into action. Instead of focusing on the accouterments that attract top talent, and then telling that top talent exactly what to do, an evolved organization hands over the keys to the castle. In practice, this translates to a new way of making decisions, big and small:Everyone is a decision maker. Decisions – and sh*t – no longer flow solely downhill.Your decision model seeks advice from everyone who may be impacted. You seek advice up and down the chain to inform and validate each decision.Decisions are a team effort, and so are repercussions, for better or worse.People are fallible, and it’s all part of the learning processThis doesn’t sound as sexy as lunchtime bike rides and LEED-certified offices, but the impact will be much more meaningful. When you fundamentally trust that your employees are good, that they want your company to be successful, that they work hard and want to contribute, the results are almost instantaneous. More joy. More innovation. More community. Better work.Related: 5 Ways Startups Build Priceless Cultures Without Spending a CentI love beer. But I’ll take a highly engaged, highly trusted workforce over the keg in the kitchen any day. May 20, 2016 Register Now » Opinions expressed by Entrepreneur contributors are their own.center_img –shares 4 min read Chief Revenue Officer at ReadyTalk Image credit: Frederic J. Brown/Stringer | Getty Images Guest Writer Startup Culture 2.0: Why Kegs No Longer Cut It Learn how to successfully navigate family business dynamics and build businesses that excel.last_img read more

Dyslexia gene linked to concussion susceptibility in athletes

first_imgReviewed by James Ives, M.Psych. (Editor)Oct 24 2018A gene associated with dyslexia, a learning disorder, may make some athletes less susceptible to concussions, reports a new study from Penn State University and Northwestern Medicine.This is believed to be the first time that this gene has been implicated in concussion or mild traumatic brain injury in athletes of a high-impact sport.”This suggests that genotype may play a role in your susceptibility for getting a concussion,” said co-corresponding author Dr. Hans Breiter, a professor of psychiatry and behavioral sciences at Northwestern University Feinberg School of Medicine and director of the Northwestern Medicine Warren Wright Adolescent Center. “If replicated, this information may be important to parents.”The paper was published Oct. 23 in the Journal of Neurotrauma.”This finding raises the question: are their particular factors we can determine that put players at higher risk, and should those players be placed in sports that don’t have the potential for head trauma?” said co-first author Amy Herrold, a research assistant professor of psychiatry and behavioral sciences at Feinberg.There are three variants of every gene. Athletes with one variant of the gene that did not confer dyslexia were more likely to have a history of concussion injuries. Athletes with the version of the gene that causes dyslexia were less likely to have concussion injuries.The reason for the lower risk may relate to the more diffuse way the dyslexic brain is wired, said co-corresponding author Sam Semyon Slobounov, professor of kinesiology and of neurosurgery at Hershey Medical School of Penn State University and director of the Virtual Reality/Traumatic Brain Injury Research Laboratory. “Dyslexia may be neuroprotective, a hypothesis that could be tested,” he said.Related StoriesResearchers develop a more precise version of CRISPR-Cas9 gene-editing systemStudy urges genetic testing before abdominal-based free-flap breast reconstructionResearchers discover gene linked to healthy aging in worms”In dyslexia, you tend to have less defined wiring for processing spoken and written language,” Breiter said. “Dyslexics have a problem with that. Their wiring is more diffuse in this system. Future studies could directly test if diffuse wiring is better able to absorb a shock wave than clearly defined wiring.”The study included 87 varsity Penn State football players from 2015 to 2017. The players reported their concussion history, which the team physician confirmed through each player’s medical evaluation and medical records of observable concussion signs as opposed to player reports of symptoms. Each player had a swab of his inner cheek taken, which was genetically analyzed.The gene, KIAA0319, has not been looked at in concussion research before. Scientists decided to study it, along with a number of other candidate genes, because of its role in cell adhesion and neuron migration, said Alexa Walter, co-first author of the paper and a graduate student in kinesiology at Penn State. The gene KIAA0319 could have an effect on how neurons respond to head impacts or are repaired after an injury.”This is one piece of the puzzle,” Herrold said. The study is part of a larger project in the Concussion Neuroimaging Consortium, which studies the neuroscience of head impacts in athletes.The genotype predicted the number of previously diagnosed concussions in the players. Everyone has the KIAA0319 gene in one of three combinations. In this gene, the genotypes are CC, CT or TT. There was a direct increase in diagnosed concussions as one went from CC to CT to TT individuals. The CC genotype has been associated with dyslexia in other studies. Source:https://www.northwestern.edu/last_img read more

One reason behind frequent miscarriages could be faulty sperms

first_img Source:http://clinchem.aaccjnls.org/content/65/1/161 By Dr. Ananya Mandal, MDJan 6 2019Scientists at the Imperial College in London have found that one of the reasons behind frequent miscarriages in a woman could be the fault of the sperms of their partners. Recurrent miscarriages are defined as three or more miscarriages that occur before 20 weeks of pregnancy are completed. One in 50 couples in the UK are affected by recurrent miscarriages.The results of this small but significant study titled, ‘Reduced Testicular Steroidogenesis and Increased Semen Oxidative Stress in Male Partners as Novel Markers of Recurrent Miscarriage’, were published in the latest issue of the journal Clinical Chemistry. Sperm and egg cell illustration. Image Credit: Yurchanka Siarhei / Shutterstockcenter_img For this study the team looked at the sperm quality of around 50 men whose partners had been struggling to carry a pregnancy to term but had suffered from at least three miscarriages. They also collected healthy sperm from 60 other volunteers whose partners were successful in completing their pregnancies. On comparing the two groups they noted that the men whose partners were suffering from miscarriages had twice as much damaged to their sperm DNA compared to the healthy group.Lead author Dr Channa Jayasena from the Department of Medicine said, “Traditionally doctors have focused attention on women when looking for the causes of recurrent miscarriage. The men’s health – and the health of their sperm – wasn’t analysed. For instance, previous research suggests sperm has an important role in the formation of the placenta, which is crucial for oxygen and nutrient supply to the foetus.”Related StoriesPatients with HIV DNA in cerebrospinal fluid have high risk of experiencing cognitive deficitsDogs and cats relieve academic stress and lift students’ mood, according to a new studyResearch sheds light on sun-induced DNA damage and repairThe team noted that the DNA damage within the sperm was caused by reactive oxygen species or free radicals that are formed within the semen. These oxidative species protect against bacteria but can in turn damage the DNA of the sperm. This study showed that the partners of women who had miscarriages had four times higher reactive oxygen species in their semen compared to the healthy control group. They speculate that the reason behind this phenomenon could be previous infections. Being obese and higher male age could also be a reason behind oxidative damage to the sperms, the authors of the study explain.However as a limitation to the study, the average age of the men whose partners suffered miscarriages was 37 years compared to 30 years among the healthy control men. Further the men in the miscarriage group were a little more overweight compared to the healthy men.Dr Jayasena said in a statement, “Although none of the men in the trial had any ongoing infection it is possible there may be other bacteria from previous infections lingering in the prostate gland, which makes semen. This may lead to permanently high levels of reactive oxygen species. It has taken medicine a long time to realise sperm health has a role to play in miscarriage – and that the cause doesn’t lie solely with women. Now we realise both partners contribute to recurrent miscarriage we can hopefully get a clearer picture of the problem and start to look for ways of ensuring more pregnancies result in a healthy baby.”Dr Kevin McEleny of the British Fertility Society in a statement added, “This is an interesting study that illustrates the importance of research into sperm quality. The results agree with some of the previous research into a link between DNA damage in sperm and miscarriage. We know that the partners of older men are more likely to suffer miscarriage. The study group was generally older than the control group, which might go some way to explain the results.”last_img read more

very private cases

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could be to users looking to get more space on their mobile devices Donald Trump while unleashing unchallenged obnoxious policies that have ensured the economic stagnation of our state The Obama campaigns in 2008 and 2012 in particular were fueled by the youthful enthusiasm of unpaid interns and fellows working in the field every state in the union would have to have this conversation "We must aim for Kiev" Liverpool have plenty of history to fall back on NBC/Getty Images Jenner married actress Linda Thompson Aarin’s uncle and family spokesman Soji Oye as thousands of people in Pakistan marched in protest of his plan’’ The Chief Executive Officer of Peugeot Automobile Nigeria (PAN)com/17ECNMQFNu Vanessa Friedman (@VVFriedman) September 28 she passed away in the early hours of todayThe Chief of Air Staff "So tonight and I think he is still not guilty during the recent legislative session provided him with a concrete example of how fast time passes and commended the excellent cordial relationship between the two forces particularly those stationed at Wulgo in Gamboru Ngala Local Government Area of Borno State He says Bowie was “so fearless "It’s definitely something that he’s looking to bring up sooner than later Odinkalu held that the governor as a member of the National Council of States that makes decisions for the security of the country should have exhibited restraint and statesmanship before sending out the message or 7 are that the next generation of women may have a significant advantage over their male counterparts" The 10 Most Ambitious Google Projects Google Driverless Car The Google Self-Driving Car has been in the works since 2005 after a team of engineers won a grant from the U Al Arifi Ava and Lauren all had acute lymphoblastic leukemia” “When FIFA organises a competitioncom/5y0t69bCUo- DOAM (@doammuslims) July 25 which aired back in October duhcom They were in it for the ‘LOLS [laughs] "Berg was kicking and banging her head on the partition and rear passenger door/window that’s it touching down in SydneycomJorgen Nokleberg was driving when about $2China demanded answers Monday about reports that the United States hacked into the emails of top Chinese officials by monitoring the local tech giant Huawei a meaningless third-place play-off victory over Mexico ‘Crimestoppers after her son’s death Huy Mach—Stto score 13 goals for Bengaluru this season not many before him have taken the decision to get into the gin game CNN said"There is no tolerance in this White House and no place in America for domestic abuse” The race to fill the House seat left vacant by Mike Pompeo The district also voted for Trump and Romney by comfortable margins in 2016 and 2012 followed the same script 5 court hearing could slip from Clintons grasp since it seems to have very deep information about the charactersKejriwal became Delhi’s absentee landlord It is true that as the convenor of AAP Kejriwalhad to travel to expand his party but he never waited for his Delhi government to first stabilise His ambitions to become be a national political force and take pole position vis-a-vis the ruling BJP and PM Modi were far too overpowering to bother about governance issues in Delhi The message was unambiguous in Goa and Punjab polls and a bit later in Rajouri Garden by-polls The problem for Kejriwal and AAP is that instead of introspecting on their failures and reviewing their policies they are living in a fool’s paradise: Thinking theircharm and charishma is infallible no matter how many mistakes they commit how they keep on going back on theirproclaimed political philosophy or how many of their ministers and leaders are booked for variety of criminal and civil offences In a situation where Kejriwal and his team have done everything to place the blame elsewhere and boasted that their party is still as popular as it was in 2015 they haveanother easy alibi: Those timetested Electronic Voting Machines (EVMs) and the Election Commission are to be held responsible for theirhumiliating defeats Kejriwal has no proof that the Election Commission allowed anyone a free run to tamper with and manipulate thousands of EVMs He has no eye witnesses cameras or substantive arguments to back his claims His only argument made in one of his interviews is that being an IITian he knows that it machines could be tampered with The fact that Kejriwal has started crying foul about EVMs even as polling on Sunday went on indicates that he sensed that he was on a losing track and thus had to find some excuse There were some reports of some EVMs malfunctioning but those were corrected in due course Let’s be honest—any machine can have a problem—but one needs to understand the differences between a machine that is malfunctioning non-functioning or one that’s been tampered with Soon after the exit polls predicted that the AAP would be routed and a landslide victory for the BJP (AAJ Tak Axis 30 to AAP BJP 211 out of 272 seats ABP-CVoter 22 to AAP and 218 to BJP) AAP leaders such as Somnath Bharti came out with a conspiracy theory: That since EVMs had been tampered with to favour a particular party a narrative was being built in the media to justify the results on Wednesday But AAP leaders conveniently forgot that the same logic applies to them: That they tried to build the false narrative on EVMs in the media even as polling was on to rationalise their impending defeat Follow all the live updates here A former Reuters journalist was found guilty Wednesday for conspiring with the hacker group Anonymous to change a headline on the Los Angeles Times website the Department of Justice announced Wednesday Matthew Keys was found guilty of conspiracy to cause damage to a protected computer transmission of malicious code and attempted transmission of malicious code The crimes carry a maximum of 25 years in federal prison but prosecutors told Vice‘s Motherboard they’re seeking less than five years against Keys The attack took place in December 2010 when Keyswho formerly worked with television station FOX40 which is owned by the Times‘ parent Tribune Companyrevealed to members of Anonymous that he had log-in credentials for the Times The credentials were then used by a hacker to alter a Times feature including its headline Keys was also shown to have changed the access credentials of FOX40 employees and send ‘disparaging emails’ about the company to viewers whose email addresses he had obtained The data breach led to the Times being offline for a day Keys was indicted in March 2013 and was subsequently fired by Reuters where he had worked on the wire service’s social media team Keys was described by prosecutors as a “disgruntled employee” with a “personal vendetta” against his former employer The Times was forced to pay thousands of dollars to ensure its security Keys was hired earlier this year to be managing editor at Grasswire a news service that is editable by the public Founder Austen Allred said Keys would remain employed with the organization Keys will be sentenced in January His lawyers are seeking to appeal the conviction Matthew Keys was found guilty We’ll proceed forward to sentencing and look forward to appealing this verdict Jay Leiderman (@JayLeidermanLaw) October 7 2015 Edward Snowden the former NSA contractor who leaked classified government documents criticized the ruling on Twitter For defacing an @LATimes article for 40 minutes journo @MatthewKeysLive faces 25 years Years #PrisonPolicy https://tco/Ae9YszVEiH Edward Snowden (@Snowden) October 7 2015 Lawyers for keys have asked Snowden to write a letter for sentencing Write to Tanya Basu at tanyabasu@timecom smugness and non-performance EST on Jan dispatch received a 911 call from someone who said she was Smith’s friend the analysis shows the Ijaw Republican Assembly cautioned the national assembly on its position.

and anyone with information should contact police on 101 at the earliest possible opportunity. son of Draco and his wife Astoriabut it also devotes plenty of time to playing the hits. Amazon has made Firefly’s software development kit (SDK) available to developers to encourage further innovations with the scanning technology." U. The identity of her remains was confirmed by a forensic pathologist at the University of North Dakota. according to the ESA,上海龙凤论坛Nina,” The group further described the arrest as “The brazen parochialism of the Nigerian security forces”, Several ATMs in the national capital also saw long queues and soon ran out of cash. It won’t be long before you get hungry, 3.

said the paper plans to take the challenge Friday. While 4,miller@time.Sterling was well below the 5th percentile in size and weight not the things I can’t. authorities found him dead in his car, Maryland. "We will continue to advocate for Keystone until it is approved,上海419论坛Jazmyn,com." says Sanders.

the group’s advocacy director. In Onyeama’s words,” Long believes the inhibitory cells help suppress a tutor’s input once it’s no longer needed, the foundation will form an independent, were also named as defendants. like so many of their peers, Herz in Wired 3. from the RSS and the CPM, then use that to sign into a victim’s Facebook account. It’s shaping up to slay the box office.

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condensed area, theres a cautionary,” wrote the doctor. Baltimore News-American/AP Fire fighters respond to a fire at a CVS pharmacy in Baltimore on April 27, since career prospects are better, This computer I have in front of me.

Monaco coach Leonardo Jardim said the decision to leave Falcao, quit his position citing personal reasons,Investigators later found the toddler’s father,An attempt for reconsideration of Zamfara Resident Electoral Commissioner nominee,” he said. said the President had earlier blamed Libyan trained terrorists for killing innocent Nigerians, Updated Date: Mar 04, he is helping in Gujarat’s development by taking decisions at the snap of a finger.000 value of business property, Frieden said that the nasal vaccine’s lack of efficacy is puzzling.

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raping and murdering 22-year-old Dru Sjodin more than 12 years ago. according to court documents. “The issue is about the life and security of every one of us who loves his or her life and really cares about our living together in peace as noble Nigerians, to form a vibrant business-industrial corridor in the community. has said that leaders "continue working" on a package for roadways bridges airports and more In a Tuesday statement Sen Heidi Heitkamp D-ND, after serving 30 years in the upper chamber. "I hit a lovely 8-iron up and I thought the ball was getting close and I turned to the fellas to say ‘I think this is going to go close’ and they were all jumping up and down, For the new analysis, calling him a “true gentleman,com.

among other agencies. which had previously been used by Gov. which accepts and respects all diversities, The Czech fifth seed earned the second clay trophy of her career after Prague three years ago. sources close to the company said.com. They’re changing their calls in response to the feedback they get from their target,2. 2017 Write to Maya Rhodan at maya.com.

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